Environmental Risk Factors.
According to National Resource Center, there is a less chance of lupus being pass down in families. Relatives of people with lupus have a 5 to 13 percent chance of developing Lupus while children of those with Lupus have a 5 percent chance of developing Lupus. In 2010, a conducted research concluded that there were about 30 genes that were linked to Lupus. By now, the numbers should have risen. Whether you get mild or severe symptoms depends on the gene variation. Environmental factors that trigger this gene variation are drugs, certain types of medication, infections and sometimes stress. Lupus is not contagious; hence that fact that it cannot be sexually transmitted. Researchers explanation to why lupus occurs more in females than males is that females have more estrogen in them than males do. Yet, there is a lacking evidence how the estrogen and lupus relate.
Genetic Risk Factors.
Lupus is not linked to a direct gene; it is linked with about a dozen more. The main gene that affects and triggers lupus the most is MHC. The normal function of this gene is to help shape the immune system and create proteins that protect the body form invaders. There are two types of the MHC gene: MHC II and MHC III. MHC II responds based on the type of ethnicity while MHC III gene codes for components of a group of proteins that interact to clear immune complex. Genes that have any contact or relationship with the immune systems is said to either cause or trigger lupus. Those with lupus tend to have other family members that have at least one kind of autoimmune disorder or disease.
According to National Resource Center, there is a less chance of lupus being pass down in families. Relatives of people with lupus have a 5 to 13 percent chance of developing Lupus while children of those with Lupus have a 5 percent chance of developing Lupus. In 2010, a conducted research concluded that there were about 30 genes that were linked to Lupus. By now, the numbers should have risen. Whether you get mild or severe symptoms depends on the gene variation. Environmental factors that trigger this gene variation are drugs, certain types of medication, infections and sometimes stress. Lupus is not contagious; hence that fact that it cannot be sexually transmitted. Researchers explanation to why lupus occurs more in females than males is that females have more estrogen in them than males do. Yet, there is a lacking evidence how the estrogen and lupus relate.
Genetic Risk Factors.
Lupus is not linked to a direct gene; it is linked with about a dozen more. The main gene that affects and triggers lupus the most is MHC. The normal function of this gene is to help shape the immune system and create proteins that protect the body form invaders. There are two types of the MHC gene: MHC II and MHC III. MHC II responds based on the type of ethnicity while MHC III gene codes for components of a group of proteins that interact to clear immune complex. Genes that have any contact or relationship with the immune systems is said to either cause or trigger lupus. Those with lupus tend to have other family members that have at least one kind of autoimmune disorder or disease.
Lupus Foundation of America(2013). What is Lupus?
http://resources.lupus.org/entry/what-is-lupus
The John Hopkins Lupus Center(ND). Causes of lupus.
https://www.hopkinslupus.org/lupus-info/lupus/
http://resources.lupus.org/entry/what-is-lupus
The John Hopkins Lupus Center(ND). Causes of lupus.
https://www.hopkinslupus.org/lupus-info/lupus/